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An antibody screen is positive only at AHG. Panel cells suggest anti-S, but dosage is suspected because homozygous S+ cells react 2+ and heterozygous S+s+ cells are nonreactive. What should the technologist do next?
Ignore the pattern because dosage is not clinically significant
Perform immediate-spin crossmatches only because anti-S reacts at AHG
Treat the panel with ficin as the only confirmation step
Test selected S-positive homozygous and S-negative cells to confirm specificity
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