Cytogenetics Technologist (CG) Practice Test

69 questions available

Build your confidence for Cytogenetics Technologist (CG). Practice the concepts, understand the answers, and strengthen your knowledge one question at a time.

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Certification exam
100 Exam questions
2 hours Time Limit
Your practice
69 Practice questions
1 hour 9 minutes Practice Time
Try 5 free questions
No account needed. A free account includes 20 questions for this exam.
The bar to clear 400 Published passing score for this certification.
Official objectives from ASCP Board of Certification
ASCP Board of Certification69 practice questions

Exam overview and details

The Cytogenetics Technologist CG Practice Test is a comprehensive assessment tool designed for clinical laboratory scientists, cytogenetic technologists, and students preparing for certification or competency evaluation in the field of cytogenetics. This 69-question exam covers four core domains: Chromosome Analysis, Cytogenetics Interpretation, Laboratory Operations, and Specimen Processing. The test evaluates a candidate's ability to perform and interpret karyotyping, fluorescence in situ hybridization (FISH), and chromosomal microarray analysis, as well as their understanding of quality control, regulatory compliance, and specimen handling protocols. It is intended for practicing technologists seeking to validate their knowledge, individuals preparing for the American Society for Clinical Pathology (ASCP) Technologist in Cytogenetics (CG) certification exam, and laboratory supervisors assessing staff readiness. By taking this practice test, users will gain a clear understanding of their strengths and weaknesses across key subject areas, improve their test-taking endurance, and build confidence in applying theoretical knowledge to real-world laboratory scenarios. The content reflects current best practices and standards from CLIA, CAP, and ACMG guidelines, ensuring relevance to modern clinical cytogenetics laboratories.

Sample Questions

Choose an answer and explore the explanation to see how practice works.

Chromosome Analysis

During chromosome analysis, which choice best applies to autosome and sex chromosome composition in the normal karyotype?

Chromosome Analysis

During chromosome analysis, which choice best applies to why conventional karyotyping needs dividing cells?

Chromosome Analysis

During chromosome analysis, which choice best applies to the risk of lacking a differential diagnosis?

Chromosome Analysis

A cytogenetics trainee is reviewing sex chromosome composition in typical female and male karyotypes. Which statement is accurate?

Chromosome Analysis

During chromosome analysis, which choice best applies to the established diploid chromosome number in 1956?

Career Opportunities & Salary

Median salary: $62,930– Clinical Laboratory Technologists and Technicians

Source: BLS Occupational Employment and Wage Statistics, May 2025 -- Clinical Laboratory Technologists and Technicians (SOC 29-2010), US national. Occupation median, not a certification salary. (2025)

Clinical Laboratory Technologists and Technicians

Exam insights and study advice

Cytogenetics technologists play a critical role in diagnosing genetic disorders, hematologic malignancies, and congenital abnormalities. Errors in chromosome analysis or interpretation can lead to misdiagnosis, inappropriate treatment, or missed therapeutic windows. This practice test directly impacts patient care by reinforcing the precision and analytical rigor required in the laboratory. Mastery of these topics ensures that technologists can accurately identify structural and numerical chromosomal abnormalities, properly process and culture specimens, and maintain compliance with regulatory standards. The practical value extends beyond exam preparation: it sharpens the skills needed to troubleshoot failed cultures, recognize artifacts, and communicate findings effectively with genetic counselors and physicians. For laboratory managers, this test serves as a benchmark for staff competency and a tool for identifying areas needing continuing education.

These are the backgrounds the certifying body suggests. Check the vendor's own page for anything it formally requires.

What this exam covers

Use the published domain weights to plan your study. Practice results do not predict your certification exam score.

01Chromosome Analysis

45-50%

02Specimen Processing

20-25%

03Laboratory Operations

10-15%

04Cytogenetics Interpretation

Exam Details CG | $135 USD | 2 hours

Exam Code CG
Vendor ASCP Board of Certification
Exam Cost $135 USD
Passing Score 400
Time Limit 2 hours
Exam questions 100
Question TypesMultiple Choice (single best answer)
Retake Policy Candidates must wait 90 days between attempts. Maximum of 6 total attempts per credential. Full exam fee required for each attempt.
Exam Format Linear fixed-form computer-based examination (CBE)
Online Proctoring Available
Exam rules Closed-book computer-based examination. On-screen calculator provided for applicable questions. Score scale 100–999; passing score is 400 for most credentials. Exams administered through ASCP's own online platform.
Available In
English

Frequently Asked Questions

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Does this test cover FISH and microarray interpretation in detail?