Praxis Chemistry: Content Knowledge (5245) Practice Test

140 questions available

Build your confidence for Praxis Chemistry: Content Knowledge (5245). Practice the concepts, understand the answers, and strengthen your knowledge one question at a time.

Try a sample question
Try 5 free questions
No account needed. A free account includes 20 questions for this exam.
Certification exam
125 Exam questions
2 hours 30 minutes Time Limit
Your practice
140 Practice questions
2 hours 20 minutes Practice Time
Try 5 free questions
No account needed. A free account includes 20 questions for this exam.
The bank 140 Practice questions checked against the official objectives.
ETS140 practice questions
Blueprint verifiedChecked against ETS official objectivesMetadata verified 2026-09-17How we verify

Exam overview and details

The Praxis Chemistry: Content Knowledge (5245) examination is a rigorous, nationally recognized certification assessment for prospective secondary school chemistry teachers. Administered by Educational Testing Service (ETS), this 2.5-hour, 120-question computer-delivered test validates a candidate's mastery of the core principles and practices essential for effective chemistry instruction. Achieving a passing score, as determined by individual state licensing boards, is a critical step toward obtaining state certification or licensure to teach chemistry at the secondary level. The exam's comprehensive scope ensures that certified educators possess not only deep subject-matter expertise but also the ability to apply chemical concepts in pedagogical contexts. This certification serves as a benchmark of professional competency, signaling to school districts, administrators, and peers that an educator meets high standards of content knowledge and is prepared to foster student understanding in a critical STEM discipline.

Sample Questions

Choose an answer and explore the explanation to see how practice works.

Nomenclature; Chemical Composition; Bonding and Structure

A student says CCl4 is polar because each C-Cl bond is polar. Which teacher response is best?

Scientific Inquiry and Social Perspectives of Science

A school board compares coal, nuclear, wind, and solar power for a chemistry-and-society lesson. Which statement best models a balanced chemistry-based tradeoff?

Chemical Reactions; Periodicity

A student heats calcium carbonate and observes formation of calcium oxide and carbon dioxide. Which reaction type is represented?

Chemical Reactions; Periodicity

A redox problem includes MnO4- forming MnO2 in basic solution. What happens to manganese's oxidation state?

Atomic and Nuclear Structure

A student balances the nuclear reaction 27Al + 4He -> 30P + ?. Which missing particle conserves both mass number and atomic number?

Exam insights and study advice

Earning a passing score on the Praxis Chemistry 5245 exam is a non-negotiable credential for professional advancement in secondary chemistry education. It is the definitive industry standard for demonstrating subject-matter expertise to state licensing agencies and prospective employers. This certification directly impacts career trajectory by qualifying candidates for licensure, a mandatory requirement for public school teaching positions. Beyond entry-level qualification, it establishes professional credibility, enhances resume competitiveness, and is often a prerequisite for career ladder advancements, such as mentoring roles or department leadership. In an educational landscape increasingly focused on STEM proficiency, this certification validates an educator's capacity to deliver accurate, engaging, and standards-aligned chemistry instruction, thereby impacting both individual career growth and the quality of science education for students.

What this exam covers

Use the published domain weights to plan your study. Practice results do not predict your certification exam score.

01Chemical Reactions; Periodicity

20%

This area covers periodic trends, chemical reaction types, kinetics, and equilibrium principles, requiring candidates to perform stoichiometric calculations, analyze limiting reagents, apply Le Châtelier’s principle, and understand the mechanisms of various oxidation-reduction chemical reactions.

02Nomenclature; Chemical Composition Structure

15%

This domain addresses chemical nomenclature, composition, and the relationship between bonding and molecular structure, requiring candidates to apply the mole concept and use Lewis structures to predict the geometry and interactions of molecules.

03Solutions and Solubility; Acid-Base Chemistry

15%

This domain involves solution chemistry, solubility rules, and the principles of acid-base interactions, requiring candidates to calculate pH and pOH, understand colligative properties, and manage the behavior of buffer solutions during various titration procedures.

04Basic Principles of Matter and Energy; Thermodynamics

14%

This domain covers the fundamental organization of matter, energy conservation, and thermodynamic principles in chemical systems, requiring candidates to demonstrate knowledge of how energy changes influence the physical and chemical states of various substances.

05Atomic and Nuclear Structure

12%

This section focuses on the current atomic model, electron configurations, and nuclear chemistry processes, requiring an understanding of quantum numbers, radioactive decay, and how electronic absorption and emission spectra provide evidence for atomic structure.

06Scientific Inquiry and Social Perspectives of Science

12%

This section examines the nature of scientific inquiry, experimental design, and the societal impact of chemistry, requiring candidates to evaluate hypothesis testing, understand historical developments in the field, and analyze the environmental impact of technology.

07Scientific Procedures and Techniques

12%

This domain focuses on data interpretation, laboratory safety, and the maintenance of equipment, requiring candidates to demonstrate proficiency in using significant figures, performing error analysis, and following standard laboratory safety rules and equipment protocols.

Exam Details ETS-5245 | 2 hours 30 minutes

Exam Code ETS-5245
Vendor ETS
Time Limit 2 hours 30 minutes
Exam questions 125

Frequently Asked Questions

What is the passing score for the Praxis Chemistry 5245 exam?

What content areas are covered on the exam?

How should I prepare for the exam?

Can I use a calculator on the exam?

How long are scores valid for certification purposes?