NBOME COMLEX-USA Level 1 Practice Test

140 questions available

Build your confidence for NBOME COMLEX-USA Level 1. Practice the concepts, understand the answers, and strengthen your knowledge one question at a time.

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Certification exam
320 Exam questions
9 hours Time Limit
Your practice
140 Practice questions
2 hours 20 minutes Practice Time
Try 5 free questions
No account needed. A free account includes 20 questions for this exam.
The bar to clear 400/CE, 350 for Level 3) Published passing score for this certification.
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Exam overview and details

The COMLEX-USA Level 1 is the first of three comprehensive osteopathic medical licensing examinations administered by the National Board of Osteopathic Medical Examiners (NBOME). This high-stakes, computer-based assessment evaluates a candidate's foundational biomedical and clinical science knowledge, with a distinct emphasis on osteopathic principles and patient-centered care. Success on COMLEX-USA Level 1 is a mandatory requirement for osteopathic medical licensure in the United States and serves as a critical benchmark for progression to clinical rotations. Beyond licensure, performance on this exam is a significant factor in residency program selection, as it demonstrates a candidate's mastery of the scientific fundamentals essential for safe and effective clinical practice. The exam's integrated format tests the application of knowledge across disciplines, mirroring the complexity of real-world patient presentations and preparing candidates for the next stages of their medical training.

Sample Questions

Choose an answer and explore the explanation to see how practice works.

Osteopathic Patient Care (Clinical Skills)

A 48-year-old with crushing chest pain has troponin elevation but no ST elevation. Which medication reduces mortality early unless contraindicated?

Osteopathic Manipulative Treatment (OMT) and OPP

During structural examination a physician documents tissue texture change, asymmetry, restricted motion, and tenderness at T5. Which osteopathic diagnostic acronym is being applied?

Osteopathic Manipulative Treatment (OMT) and OPP

A physician engages the restrictive barrier of a rotated thoracic segment and asks the patient to gently rotate against resistance before relaxing. Which technique is this?

Osteopathic Medical Knowledge (Biomedical Sciences)

A 34-year-old with type 1 diabetes has nausea, Kussmaul respirations, glucose 410 mg/dL, bicarbonate 9 mEq/L, and potassium 5.8 mEq/L. After fluids, which treatment must not be delayed because it closes the anion gap?

Osteopathic Manipulative Treatment (OMT) and OPP

A 72-year-old with severe osteoporosis has acute rib pain after coughing and restricted thoracic motion. Which OMT choice is safest?

Exam insights and study advice

Achieving a strong score on COMLEX-USA Level 1 is paramount for career advancement in osteopathic medicine. It is the primary standardized metric used by residency program directors to assess the academic preparedness of applicants. A competitive performance not only fulfills a core licensure requirement but also significantly enhances your candidacy for sought-after residency positions across all specialties. This certification validates your foundational medical competency to the industry, establishing credibility and opening doors to future training opportunities essential for a successful medical career.

These are the backgrounds the certifying body suggests. Check the vendor's own page for anything it formally requires.

What this exam covers

01Anatomy and Embryology

02Behavioral Sciences and Biostatistics

03Organ Systems (cardiovascular, pulmonary, GI, renal, neuro, MSK, reproductive, endocrine)

04Osteopathic Principles, Practices, and Manipulative Medicine

05Pathology and Microbiology

06Pharmacology and Therapeutics

Exam Details COMLEX-USA Level 1 | $665 USD | 9 hours

Exam Code COMLEX-USA Level 1
Vendor NBOME
Exam Cost $665 USD
Passing Score 400/CE, 350 for Level 3)
Time Limit 9 hours
Exam questions 320
Question TypesMultiple Choice, Single Best Answer, OSCE (Level 2-PE, suspended)
Retake Policy 60-day waiting period between failed attempts. Maximum 4 attempts per COMLEX-USA level. Candidates who exhaust attempts must petition NBOME for additional eligibility.
Exam Format Linear computer-based (Levels 1, 2-CE, 3 at Prometric); OSCE (Level 2-PE, suspended)

Frequently Asked Questions

What is the primary purpose of the COMLEX-USA Level 1 exam?

How is Osteopathic Principles and Practice (OPP) integrated into the exam?

How does COMLEX-USA Level 1 differ from USMLE Step 1?

What is the passing score and how is the exam scored?

When should I take COMLEX-USA Level 1, and what is the best preparation strategy?